# NIOSH Pocket Guide to Chemical Hazards
Nicotine | CAS 54-11-5
C5H4NC4H7NCH3 | RTECS QS5250000
Synonyms & Trade Names 3-(1-Methyl-2-pyrrolidyl)pyridine | DOT ID & Guide 1654 151
Exposure Limits | NIOSH REL: TWA 0.5 mg/m3 [skin]
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH 5 mg/m3 | Conversion
Physical Description Pale-yellow to dark-brown liquid with a fish-like odor when warm. [insecticide]
MW: 162.2 | BP: 482°F (Decomposes) | FRZ: -110°F | Sol: Miscible
VP: 0.08 mmHg | IP: 8.01 eV |  | Sp.Gr: 1.01
Fl.P: 203°F | UEL: 4.0% | LEL: 0.7% |
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities Strong oxidizers, strong acids
Measurement Methods NIOSH 2544, 2551
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: No recommendation Provide: Eyewash, Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA Up to 5 mg/m3: (APF = 10) Any supplied-air respirator/(APF = 50) Any self-contained breathing apparatus with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Nausea, salivation, abdominal pain, vomiting, diarrhea; headache, dizziness, hearing, visual disturbance; confusion, lassitude (weakness, exhaustion), incoordination; cardiac arrhythmias; convulsions, dyspnea (breathing difficulty); in animals: teratogenic effects
Target Organs central nervous system, cardiovascular system, lungs, gastrointestinal tract, reproductive system
See also: INTRODUCTION