# NIOSH Pocket Guide to Chemical Hazards
Xylidine | CAS 1300-73-8
(CH3)2C6H3NH2 | RTECS ZE8575000
Synonyms & Trade Names Aminodimethylbenzene, Aminoxylene, Dimethylaminobenzene, Dimethylaniline, Xylidine isomers (e.g., 2,4-Dimethylaniline) [Note: Dimethylaniline is also used as a synonym for N,N-Dimethylaniline.] | DOT ID & Guide 1711 153
Exposure Limits | NIOSH REL: TWA 2 ppm (10 mg/m3) [skin]
OSHA PEL†: TWA 5 ppm (25 mg/m3) [skin]
IDLH 50 ppm | Conversion 1 ppm = 4.96 mg/m3
Physical Description Pale-yellow to brown liquid with a weak, aromatic, amine-like odor.
MW: 121.2 | BP: 415-439°F | FRZ: -33°F | Sol: Slight
VP: <1 mmHg | IP: 7.65 eV (2,4-) 7.30 eV (2,6-) |  | Sp.Gr: 0.98
Fl.P: 206°F (2,3-) | UEL: ? | LEL: 1.0% (o-isomer) |
Class IIIB Combustible Liquid (2,3-)
Incompatibilities & Reactivities Strong oxidizers, hypochlorite salts
Measurement Methods NIOSH 2002
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: No recommendation Provide: Eyewash, Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH Up to 20 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)/(APF = 10) Any supplied-air respirator Up to 50 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Anoxia, cyanosis, methemoglobinemia; lung, liver, kidney damage
Target Organs respiratory system, blood, liver, kidneys, cardiovascular system
See also: INTRODUCTION