# NIOSH Pocket Guide to Chemical Hazards
Dimethylformamide | CAS 68-12-2
HCON(CH3)2 | RTECS LQ2100000
Synonyms & Trade Names Dimethyl formamide; N,N-Dimethylformamide; DMF | DOT ID & Guide 2265 129
Exposure Limits | NIOSH REL: TWA 10 ppm (30 mg/m3) [skin]
OSHA PEL: TWA 10 ppm (30 mg/m3) [skin]
IDLH 500 ppm | Conversion 1 ppm = 2.99 mg/m3
Physical Description Colorless to pale-yellow liquid with a faint, amine-like odor.
MW: 73.1 | BP: 307°F | FRZ: -78°F | Sol: Miscible
VP: 3 mmHg | IP: 9.12 eV |  | Sp.Gr: 0.95
Fl.P: 136°F | UEL: 15.2% | LEL(212°F): 2.2% |
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
Incompatibilities & Reactivities Carbon tetrachloride; other halogenated compounds when in contact with iron; strong oxidizers; alkyl aluminums; inorganic nitrates
Measurement Methods NIOSH 2004; OSHA 66
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: No recommendation | First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush promptly Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH Up to 100 ppm: (APF = 10) Any supplied-air respirator* Up to 250 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode* Up to 500 ppm: (APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode*/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, respiratory system; nausea, vomiting, colic; liver damage, enlarged liver; high blood pressure; face flush; dermatitis; in animals: kidney, heart damage
Target Organs Eyes, skin, respiratory system, liver, kidneys, cardiovascular system
See also: INTRODUCTION