# NIOSH Pocket Guide to Chemical Hazards
Dimethyl acetamide | CAS 127-19-5
CH3CON(CH3)2 | RTECS AB7700000
Synonyms & Trade Names N,N-Dimethyl acetamide; DMAC | DOT ID & Guide
Exposure Limits | NIOSH REL: TWA 10 ppm (35 mg/m3) [skin]
OSHA PEL: TWA 10 ppm (35 mg/m3) [skin]
IDLH 300 ppm | Conversion 1 ppm = 3.56 mg/m3
Physical Description Colorless liquid with a weak, ammonia- or fish-like odor.
MW: 87.1 | BP: 329°F | FRZ: -4°F | Sol: Miscible
VP: 2 mmHg | IP: 8.81 eV |  | Sp.Gr: 0.94
Fl.P(oc): 158°F | UEL(320°F): 11.5% | LEL(212°F): 1.8% |
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Incompatibilities & Reactivities Carbon tetrachloride, other halogenated compounds when in contact with iron, oxidizers
Measurement Methods NIOSH 2004
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: No recommendation Provide: Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA Up to 100 ppm: (APF = 10) Any supplied-air respirator Up to 250 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode Up to 300 ppm: (APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation skin; jaundice, liver damage; depression, drowsiness, hallucinations, delusions
Target Organs Skin, liver, central nervous system
See also: INTRODUCTION