# NIOSH Pocket Guide to Chemical Hazards
p-Anisidine | CAS 104-94-9
NH2C6H4OCH3 | RTECS BZ5450000
Synonyms & Trade Names para-Aminoanisole, 4-Anisidine, p-Methoxyaniline | DOT ID & Guide 2431 153
Exposure Limits | NIOSH REL: TWA 0.5 mg/m3 [skin]
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH 50 mg/m3 | Conversion
Physical Description Yellow to brown, crystalline solid with an amine-like odor.
MW: 123.2 | BP: 475°F | MLT: 135°F | Sol: Moderate
VP(77°F): 0.006 mmHg | IP: 7.44 eV |  | Sp.Gr: 1.07
Fl.P: ? | UEL: ? | LEL: ? |
Combustible Solid
Incompatibilities & Reactivities Strong oxidizers
Measurement Methods NIOSH 2514
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: Daily Provide: Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA Up to 5 mg/m3: (APF = 10) Any dust and mist respirator except single-use and quarter-mask respirators/(APF = 10) Any supplied-air respirator Up to 12.5 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with a dust and mist filter Up to 25 mg/m3: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter*/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Up to 50 mg/m3: (APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode* Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, dizziness; cyanosis; red blood cell Heinz bodies
Target Organs Blood, kidneys, liver, cardiovascular system, central nervous system
See also: INTRODUCTION