# NIOSH Pocket Guide to Chemical Hazards
Hexafluoroacetone | CAS 684-16-2
(CF3)2CO | RTECS UC2450000
Synonyms & Trade Names Hexafluoro-2-propanone; 1,1,1,3,3,3-Hexafluoro-2-propanone; HFA; Perfluoroacetone | DOT ID & Guide 2420 125
Exposure Limits | NIOSH REL: TWA 0.1 ppm (0.7 mg/m3) [skin]
OSHA PEL†: none
IDLH N.D. | Conversion 1 ppm = 6.79 mg/m3
Physical Description Colorless gas with a musty odor. [Note: Shipped as a liquefied compressed gas.]
MW: 166.0 | BP: -18°F | FRZ: -188°F | Sol: Reacts
VP: 5.8 atm | IP: 11.81 eV | RGasD: 5.76 |
Fl.P: NA | UEL: NA | LEL: NA |
Nonflammable Gas, but highly reactive with water & other substances, releasing heat.
Incompatibilities & Reactivities Water, acids [Note: Hygroscopic (i.e., absorbs moisture from the air); reacts with moisture to form a highly acidic sesquihydrate.]
Measurement Methods None available
Personal Protection & Sanitation Skin: Prevent skin contact/Frostbite Eyes: Prevent eye contact/Frostbite Wash skin: No recommendation Remove: No recommendation Change: No recommendation Provide: Frostbite | First Aid (See procedures) Eye: Frostbite Skin: Frostbite Breathing: Respiratory support
Respirator Recommendations To be added later
Exposure Routes inhalation, skin absorption, skin and/or eye contact
Symptoms Irritation eyes, skin, mucous membrane, respiratory system; pulmonary edema; liquid: frostbite; in animals: teratogenic, reproductive effects; kidney injury
Target Organs Eyes, skin, respiratory system, kidneys, reproductive system
See also: INTRODUCTION