# NIOSH Pocket Guide to Chemical Hazards
Kepone | CAS 143-50-0
C10Cl10O | RTECS PC8575000
Synonyms & Trade Names Chlordecone; Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)-pentalen-2-one; Decachlorooctahydro-kepone-2-one; Decachlorotetrahydro-4,7-methanoindeneone | DOT ID & Guide
Exposure Limits | NIOSH REL: Ca TWA 0.001 mg/m3 See Appendix A
OSHA PEL: none
IDLH Ca [N.D.] | Conversion
Physical Description Tan to white, crystalline, odorless solid. [insecticide]
MW: 490.6 | BP: Sublimes | MLT: 662°F (Sublimes) | Sol(212°F): 0.5%
VP(77°F): 3 x 10-7 mmHg | IP: ? |  | Sp.Gr: ?
Fl.P: NA | UEL: NA | LEL: NA |
Noncombustible Solid
Incompatibilities & Reactivities Acids, acid fumes
Measurement Methods NIOSH 5508
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated/Daily Remove: When wet or contaminated Change: Daily Provide: Eyewash, Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, anxiety, tremor; liver, kidney damage; visual disturbance; ataxia, chest pain, skin erythema (skin redness); testicular atrophy, low sperm count; [potential occupational carcinogen]
Target Organs Eyes, skin, respiratory system, central nervous system, liver, kidneys, reproductive system Cancer Site [in animal: liver cancer]
See also: INTRODUCTION