# NIOSH Pocket Guide to Chemical Hazards
p-Nitroaniline | CAS 100-01-6
NO2C6H4NH2 | RTECS BY7000000
Synonyms & Trade Names para-Aminonitrobenzene, 4-Nitroaniline, 4-Nitrobenzenamine, p-Nitrophenylamine, PNA | DOT ID & Guide 1661 153
Exposure Limits | NIOSH REL: TWA 3 mg/m3 [skin]
OSHA PEL†: TWA 6 mg/m3 (1 ppm) [skin]
IDLH 300 mg/m3 | Conversion
Physical Description Bright yellow, crystalline powder with a slight ammonia-like odor.
MW: 138.1 | BP: 630°F | MLT: 295°F | Sol: 0.08%
VP: 0.00002 mmHg | IP: 8.85 eV |  | Sp.Gr: 1.42
Fl.P: 390°F | UEL: ? | LEL: ? |
Combustible Solid
Incompatibilities & Reactivities Strong oxidizers, strong reducers [Note: May result in spontaneous heating of organic materials in the presence of moisture.]
Measurement Methods NIOSH 5033
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated/Daily Remove: When wet or contaminated Change: Daily Provide: Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH Up to 30 mg/m3: (APF = 10) Any supplied-air respirator* Up to 75 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode* Up to 150 mg/m3: (APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Up to 300 mg/m3: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister in combination with a dust, mist, and fume filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation nose, throat; cyanosis, ataxia; tachycardia, tachypnea; dyspnea (breathing difficulty); irritability; vomiting, diarrhea; convulsions; respiratory arrest; anemia; methemoglobinemia; jaundice
Target Organs respiratory system, blood, heart, liver
See also: INTRODUCTION