# NIOSH Pocket Guide to Chemical Hazards
Isopropyl acetate | CAS 108-21-4
CH3COOCH(CH3)2 | RTECS AI4930000
Synonyms & Trade Names Isopropyl ester of acetic acid, 1-Methylethyl ester of acetic acid, 2-Propyl acetate | DOT ID & Guide 1220 129
Exposure Limits | NIOSH REL: See Appendix D
OSHA PEL†: TWA 250 ppm (950 mg/m3)
IDLH 1800 ppm | Conversion 1 ppm = 4.18 mg/m3
Physical Description Colorless liquid with a fruity odor.
MW: 102.2 | BP: 194°F | FRZ: -92°F | Sol: 3%
VP: 42 mmHg | IP: 9.95 eV |  | Sp.Gr: 0.87
Fl.P: 36°F | UEL: 8% | LEL(100°F): 1.8% |
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities Nitrates; strong oxidizers, alkalis & acids
Measurement Methods NIOSH 1454; OSHA 7
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet (flammable) Change: No recommendation | First Aid (See procedures) Eye: Irrigate immediately Skin: Water flush promptly Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations OSHA Up to 1800 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, nose; dermatitis; in animals: narcosis
Target Organs Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION