# NIOSH Pocket Guide to Chemical Hazards
p-Toluidine | CAS 106-49-0
CH3C6H4NH2 | RTECS XU3150000
Synonyms & Trade Names 4-Aminotoluene, 4-Methylaniline, 4-Methylbenzenamine, 4-Toluidine, Tolylamine | DOT ID & Guide 1708 153
Exposure Limits | NIOSH REL: Ca See Appendix A
OSHA PEL†: none
IDLH Ca [N.D.] | Conversion
Physical Description White solid with an aromatic odor. [Note: Used as a basis for many dyes.]
MW: 107.2 | BP: 393°F | MLT: 111°F | Sol: 0.7%
VP(108°F): 1 mmHg | IP: 7.50 eV |  | Sp.Gr: 1.05
Fl.P: 188°F | UEL: ? | LEL: ? |
Combustible Solid
Incompatibilities & Reactivities Oxidizers, acids
Measurement Methods NIOSH 2002; OSHA 73
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated/Daily Remove: When wet or contaminated Change: Daily Provide: Eyewash, Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin; dermatitis; hematuria (blood in the urine), methemoglobinemia; cyanosis, nausea, vomiting, low blood pressure, convulsions; anemia, lassitude (weakness, exhaustion); [potential occupational carcinogen]
Target Organs Eyes, skin, blood, cardiovascular system Cancer Site [in animals: liver tumors]
See also: INTRODUCTION