# NIOSH Pocket Guide to Chemical Hazards
Acetone | CAS 67-64-1
(CH3)2CO | RTECS AL3150000
Synonyms & Trade Names Dimethyl ketone, Ketone propane, 2-Propanone | DOT ID & Guide 1090 127
Exposure Limits | NIOSH REL: TWA 250 ppm (590 mg/m3)
OSHA PEL†: TWA 1000 ppm (2400 mg/m3)
IDLH 2500 ppm [10%LEL] | Conversion 1 ppm = 2.38 mg/m3
Physical Description Colorless liquid with a fragrant, mint-like odor.
MW: 58.1 | BP: 133°F | FRZ: -140°F | Sol: Miscible
VP: 180 mmHg | IP: 9.69 eV |  | Sp.Gr: 0.79
Fl.P: 0°F | UEL: 12.8% | LEL: 2.5% |
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities Oxidizers, acids
Measurement Methods NIOSH 1300, 3800; OSHA 69
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet (flammable) Change: No recommendation | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH Up to 2500 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 10) Any supplied-air respirator*/(APF = 50) Any self-contained breathing apparatus with a full facepiece Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, nose, throat; headache, dizziness, central nervous system depression; dermatitis
Target Organs Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION