# NIOSH Pocket Guide to Chemical Hazards
o-Anisidine | CAS 90-04-0
NH2C6H4OCH3 | RTECS BZ5410000
Synonyms & Trade Names ortho-Aminoanisole, 2-Anisidine, o-Methoxyaniline [Note: o-Anisidine has been used as a basis for many dyes.] | DOT ID & Guide 2431 153
Exposure Limits | NIOSH REL: Ca 0.5 mg/m3 [skin] See Appendix A
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH Ca [50 mg/m3] | Conversion
Physical Description Red or yellow, oily liquid with an amine-like odor. [Note: A solid below 41°F.]
MW: 123.2 | BP: 437°F | FRZ: 41°F | Sol(77°F): 1%
VP: <0.1 mmHg | IP: 7.44 eV |  | Sp.Gr: 1.10
Fl.P(oc): 244°F | UEL: ? | LEL: ? |
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities Strong oxidizers
Measurement Methods NIOSH 2514
Personal Protection & Sanitation Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated Remove: When wet or contaminated Change: Daily Provide: Eyewash, Quick drench | First Aid (See procedures) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately
Respirator Recommendations NIOSH At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, dizziness; cyanosis; red blood cell Heinz bodies; [potential occupational carcinogen]
Target Organs Blood, kidneys, liver, cardiovascular system, central nervous system Cancer Site [in animals: tumors of the thyroid gland, bladder & kidneys]
See also: INTRODUCTION